Does HSIL turn into cancer?
Moderate or severe dysplasia, called high-grade intraepithelial lesion (HSIL) is another type of dysplasia. LSIL and HSIL may or may not become cancer.
Should I be worried if I have HSIL?
High-Grade Squamous Intraepithelial Lesions (HSIL) means there are moderately or severely abnormal cervical cells that could become cancer in the future if not treated. Some lesions may be called precancer. Your health care provider will likely ask you to come back for a colposcopy, as explained on page 10.
How long does it take for HSIL to become cancer?
If left untreated, it may take 10 years or more for precancerous conditions of the cervix to turn into cervical cancer, but in rare cases this can happen in less time. Precancerous conditions of the cervix happen in an area called the transformation zone.
What is the treatment for HSIL?
HSIL (CIN2/3) Ablative methods such as CO2 laser ablation are effective but infrequently used in modern practice. Excisional methods such a large loop excision of the TZ (LLETZ), loop electrosurgical excision procedure (LEEP) or cold-knife cone biopsy are preferred.
Does HSIL mean I have HPV?
HSIL is a squamous cell abnormality associated with human papillomavirus (HPV). Though not all HSIL will progress to cancer, HSIL is considered to be a precancerous lesion and therefore is usually treated aggressively.
Is HSIL always caused by HPV?
Is HSIL the same as HPV?
What does HSIL mean on a Pap smear?
High-grade squamous intraepithelial lesions (HSIL) refer to moderate to severe changes in the cells of the cervix. If less severe changes are seen, this is called low-grade squamous intraepithelial lesions (LSIL).
How do you get HSIL?
They are usually caused by chronic infection with certain types of human papillomavirus (HPV) and are found when a Pap test or biopsy is done. If not treated, these abnormal cells may become cancer and spread into nearby tissue. A HSIL is sometimes called moderate or severe dysplasia.
How long does it take for HPV to cause HSIL?
In addition, in women with high-risk HPV infection, LSIL regresses more slowly (mean 13.8 months) and progresses more quickly (mean time to HSIL or worse 73.3 months) than in women with other HPV genotypes.
What is HSIL Pap?
An abnormal Pap smear result of high-grade squamous intraepithelial lesion (HSIL) means that cells of the cervix (the narrow neck of a woman’s uterus) look somewhat to very abnormal when examined under a microscope.
Can HSIL go away?
Because LSIL (including warts) is benign, and usually regresses on its own, it may be unnecessary to treat. However, many patients and clinicians prefer to remove warts rather than waiting for them to go away on their own.
What does HSIL and AGC mean on Pap smear?
HSIL indicates squamous cells that appear very abnormal and signify the possibility of a precancer or cancer of the cervix. AGC indicates glandular cells on a Pap test that appear abnormal. Glandular cells on a Pap test are usually cells from the cervical canal but may also come from the uterus.
What is HSIL and atypical glandular cells?
“High-grade squamous intraepithelial lesion” (HSIL) is the name given to squamous cells on a Pap test (also called a Pap smear or cervical cytology) that appear very abnormal and signify the possibility of a precancer or cancer of the cervix. “Atypical glandular cells” (AGC) is the name given to glandular cells on a Pap test that appear abnormal.
What is a low grade lesion on a Pap smear?
Low-grade lesions may also be called mild dysplasia, or CIN1. If it is your first abnormal Pap smear, your doctor will likely recommend a colposcopy. This diagnosis means the cells appear very different from normal cells. These precancerous lesions are more severe than with LSIL, but involve cells on the surface of the cervix.
Is HSIL a pre-cancer disease?
HSIL is called a pre-cancerous disease because it can turn into an invasive cancer called squamous cell carcinoma. The cells in HSIL are abnormal and look almost identical to cancer cells, however, they are only seen in the epithelium on the outer surface of the cervix. No abnormal cells are found in the stroma.