Why does artemether and lumefantrine have a combination?

Why does artemether and lumefantrine have a combination?

Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P.

What is the combination of artemether?

The combination of artemether and lumefantrine is used to treat certain kinds of malaria infections (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death). Artemether and lumefantrine should not be used to prevent malaria.

Can I take malaria drugs with antacid?

Background: Artemether-lumefantrine (A-L), an artemisinin-based combination therapy (ACT), is a widely used antimalarial drug and it could be prescribed together with antacids since malaria may co-exist with peptic ulcer.

Does artemether-lumefantrine cause diarrhea?

SIDE EFFECTS: Headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough, and trouble sleeping may occur….

System Organ Class Preferred Term Children* N = 1332 (%)
Gastrointestinal disorders Abdominal pain 112 (8)
Diarrhea 100 (8)
Nausea 61 (5)

Can I take azithromycin and artemether-lumefantrine?

azithromycin oral and artemether-lumefantrine oral both increase causing a dangerous abnormal heart rhythm. Monitor CloselyUse Caution/Monitor.

Can I take paracetamol with artemether and lumefantrine?

Interactions between your drugs No interactions were found between artemether / lumefantrine and Paracetamol.

Can I take azithromycin and artemether lumefantrine?

What is artemisinin combination?

Artemisinin-based combination therapies (ACTs) are the first-line therapy in almost all countries where malaria is endemic due to the high efficacy, tolerability, and ability of ACTs to reduce ongoing transmission of the parasite. ACTs are comprised of two components: an artemisinin derivative and a partner drug.

Can I take antacid and Coartem?

Interactions between your drugs No interactions were found between aluminum hydroxide / magnesium trisilicate and Coartem.

Does malaria drugs cause stomach pain?

GP Dr Jeff Foster says: “The most common side effects with antimalarials affect more than one in 10 people. For instance, with Malarone, these very common side effects can include headache, nausea, abdominal pain and diarrhoea.

Can malaria drugs be taken on empty stomach?

With a few exceptions, and unless stated otherwise by a doctor, most anti-malaria medications are also taken with a meal. This is important because taking medicine after a meal not only ensures that medicine is absorbed into the bloodstream but also prevents side effects, stomach irritation and ulcers.

Can you take antibiotics and malaria pills at the same time?

Antibiotics can be used in areas where parasites are resistant to standard anti-malarial drugs. This difference in modes of action also implies that antibiotics can be a good partner for combination.

Can amoxicillin be taken with artemether?

Interactions between your drugs No interactions were found between Amoxil and artemether / lumefantrine.

Why is combination therapy used in malaria?

The major reason for the great mortality caused by malaria infections globally is drug resistance [5]. Chloroquine, the most active antimalarial, suffers from drug resistance [6]. Combination therapy is a promising approach that is currently employed to overcome drug resistance [7,8].

Can I take two medications together?

It’s important to take your medication as directed by your doctor or pharmacist. If two meds interact, spacing them apart during the day may not stop them from interacting and could lead to new or worse problems. To avoid an interaction, your doctor may need to change your dose or prescribe a different medication.

Can I take malaria drugs on empty stomach?

Does malaria drug cause running stomach?