WHO recommended treatment of malaria?
Artemisinin-based combination therapies (ACTs) are the recommended treatments for uncomplicated falciparum malaria. The following ACTs are recommended: – Artemether + lumefantrine; artesunate + amodiaquine; artesunate + mefloquine; artesunate + sulfadoxine-pyrimethamine, and dihydroartemisinin + piperaquine .
What is the standard treatment of malaria?
Artemether-lumefantrine (Coartem™) is the preferred follow-on treatment but adequate alternatives are atovaquone-proguanil (Malarone™), quinine plus doxycycline or clindamycin, or mefloquine.
What is the second line treatment of malaria?
As a result, the first line treatment for uncomplicated malaria was changed to Artemisinin-based combination therapy (ACTs), with the recommended second-line therapy remaining oral quinine. The recommended ACT in Uganda is artemetherlumefantrine (AL) with the alternative of amodiaquine/artesunate (AQ/AS).
What are the names of drugs for malaria?
chloroquine (Aralen),
What is the difference between primaquine and chloroquine?
Chloroquine is a highly effective schizontocide, while primaquine has weaker asexual-stage activity (3) but is the only generally available drug with hypnozoitocidal properties, i.e., it kills dormant liver stage parasites and prevents relapse (radical cure) (1).
What are the who guidelines for the treatment of malaria?
treatment, remains a vital component of malaria control and elimination strategies. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on new evidence particularly related to dosing in children, and also includes recommendations on the use of drugs to prevent
What’s new in malaria case management?
Malaria case management, consisting of early diagnosis and prompt effective treatment, remains a vital component of malaria control and elimination strategies. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on new evidence particularly related to dosing
Which drugs are used in the treatment of malaria 3rd edition?
62 Guidelines for the treatment of malaria 3RDEDITION blood-stage infections, in addition to providing radical cure. The only drugs with significant activity against the hypnozoites are the 8-aminoquinolines (primaquine, bulaquine, tafenoquine).
What is the best malaria treatment for children with seasonal malaria?
In areas with highly seasonal malaria transmission, provide SMC with monthly amodiaquine + sulfadoxine–pyrimethamine for all children < 6 years during each transmission season. SMC prevents up to three quarters of malaria episodes (high-quality evidence