What is spironolactone used for and side effects?
Spironolactone (Aldactone) is an older medication that affects the kidneys and hormones. It’s still used today to treat several conditions, such as heart failure, high blood pressure, and fluid buildup. The most common side effects of spironolactone are high potassium levels and breast tenderness.
What is spironolactone good for?
Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Spironolactone is also used to lessen the need for hospitalization for heart failure.
Does spironolactone affect mood?
Of the individual symptoms, spironolactone significantly improved irritability, depression, feeling of swelling, breast tenderness and food craving in comparison to placebo. A lasting effect of spironolactone was observed in women started with spironolactone after cross over to placebo.
Is spironolactone high risk?
Findings In this systematic review and meta-analysis of 7 observational studies, spironolactone use was not associated with statistically significant increased risks of breast or other solid organ cancers. It was also associated with a decreased risk of prostate cancer.
Why do you have to wear gloves with spironolactone?
Wear gloves when handling Spironolactone tablets. Prolonged exposure to Spironolactone can cause birth defects, reproductive harm, cancer, or organ damage.
What happens if a man takes spironolactone?
Spironolactone also commonly and dose-dependently produces gynecomastia (breast development) as a side effect in men. At low doses, the rate is only 5 to 10%, but at high doses, up to or exceeding 50% of men may develop gynecomastia.
Does spironolactone make you feminine?
Typically, you’ll begin feminizing hormone therapy by taking the diuretic spironolactone (Aldactone) at doses of 100 to 200 milligrams daily. This blocks male sex hormone (androgen) receptors and can suppress testosterone production.
Is spironolactone an antidepressant?
Specifically, we studied the antidepressant-like effects of spironolactone (a MR antagonist), mifepristone (a GR antagonist), and the antidepressant clomipramine (CMI) administered directly into the LS.
Is spironolactone a steroid?
Spironolactone is a steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7. It has a role as a diuretic, an aldosterone antagonist, an antihypertensive agent, an environmental contaminant and a xenobiotic.
Does spironolactone make you smell?
In Warner’s experience, he’s heard that the blood pressure drug diltiazem smells “strongly like plastic,” the diuretic Spironolactone has a “minty, menthol smell,” and that the antibiotic cephalexin simply has “an awful smell.”