What is ischemia trial?

What is ischemia trial?

The purpose of the ISCHEMIA trial is to determine the best management strategy for higher-risk patients with stable ischemic heart disease (SIHD). This is a multicenter randomized controlled trial with 5179 randomized participants with moderate or severe ischemia on stress testing.

How is ischemia treated?

Treatment for myocardial ischemia involves improving blood flow to the heart muscle. Treatment may include medications, a procedure to open blocked arteries (angioplasty) or bypass surgery. Making heart-healthy lifestyle choices is important in treating and preventing myocardial ischemia.

What ischemia means?

Ischemia is a condition in which the blood flow (and thus oxygen) is restricted or reduced in a part of the body. Cardiac ischemia is the name for decreased blood flow and oxygen to the heart muscle.

What is the Courage trial?

The Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial was designed to determine whether percutaneous coronary intervention (PCI) coupled with optimal medical therapy (OMT) reduced the risk of death or nonfatal myocardial infarction in patients with stable coronary artery …

What does ischemia look like on an ECG?

Exercise ECG is widely used for the diagnosis of ischemic heart disease. The most common ECG sign of myocardial ischemia is flat or down-sloping ST-segment depression of 1.0 mm or greater.

Is a stent considered revascularization?

What Is Revascularization? Revascularization is a procedure that restores blood flow by clearing the blockage from a severely diseased artery or creating a new route. This can be done with angioplasty (possibly including stent placement) or with coronary artery bypass grafting (CABG), also called open-heart surgery.

Does ischemia go away?

Ischemia may be reversible, in which case the affected tissue will recover with the restoration of blood flow, or irreversible, which can result in tissue death.

Can you reverse ischemia?

“You can’t cure heart disease, but you can slow its progression.” Ornish agrees that if you’re just trying to slow heart disease, you might have more freedom with your diet.

Can stress cause ischemia?

Mental stress-induced myocardial ischemia (MSIMI) is a frequent phenomenon in patients with coronary artery disease (CAD) and is associated with a doubling of recurrent events and mortality, to a similar extent as ischemia provoked by a conventional stress test.

What is a high Syntax score?

The SYNTAX score is an angiographic tool to help cardiologists, interventionists and surgeons to grade the complexity of coronary artery lesions. [6] A higher SYNTAX score indicates a more complex condition as well as worse prognosis in patients undergoing contemporary revascularization especially with PCI.

How many stents can you have in one artery?

In answer to your first question, in some cases doctors can place two or even three stents during one procedure. There are, however, cases in which the cardiologist will want to place one and then place a second or even a third stent in a later procedure.