What is in situ cancer?
Carcinoma in situ (CIS) is a group of abnormal cells that are found only in the place where they first formed in the body (see left panel). These abnormal cells may become cancer and spread to nearby normal tissue (see right panel).
What stage is in situ cancer?
Carcinoma in situ is sometimes called stage 0 cancer or ‘in situ neoplasm’. It means that there is a group of abnormal cells in an area of the body. The cells may develop into cancer at some time in the future.
What is the difference between in situ and invasive cancer?
In situ breast cancer (ductal carcinoma in situ or DCIS) is a pre-cancer that starts in a milk duct and has not grown into the rest of the breast tissue. The term invasive (or infiltrating) breast cancer is used to describe any type of breast cancer that has spread (invaded) into the surrounding breast tissue.
What mean by in situ?
In its original place
Listen to pronunciation. (in SY-too) In its original place. For example, in carcinoma in situ, abnormal cells are found only in the place where they first formed.
What is in situ condition?
conditions where genetic resources exist within ecosystems and natural habitats, and, in the case of domesticated or cultivated species, in the surroundings where they have developed their distinctive properties. [
Can in situ cancer spread?
Carcinoma in situ refers to cancer in which abnormal cells have not spread beyond where they first formed. The words “in situ” mean “in its original place.” These in situ cells are not malignant, or cancerous. However, they can sometime become cancerous and spread to other nearby locations.
What is the treatment for carcinoma in situ?
TREATMENT APPROACH Patients with DCIS undergo local treatment with breast-conserving therapy (BCT) or mastectomy. BCT consists of lumpectomy (also called breast-conserving surgery, wide excision, or partial mastectomy) followed in most cases by adjuvant radiation.
What causes carcinoma in situ?
It’s not clear what causes DCIS. DCIS forms when genetic mutations occur in the DNA of breast duct cells. The genetic mutations cause the cells to appear abnormal, but the cells don’t yet have the ability to break out of the breast duct.
Is carcinoma in situ reversible?
Unlike mild or moderate dysplasia in which similar changes are seen but which involve only a portion of the thickness or depth of epithelium, carcinoma in-situ is not reversible with the elimination of the causative agent such as cigarette smoke, and eventually is expected to become invasive carcinoma.
What does in situ mean medically?
(in SY-too) In its original place. For example, in carcinoma in situ, abnormal cells are found only in the place where they first formed. They have not spread.
What is in situ in biology?
In biology and biomedical engineering, in situ means to examine the phenomenon exactly in place where it occurs (i.e., without moving it to some special medium).
Can carcinoma in situ be cured?
About 1 in 5 new breast cancers will be ductal carcinoma in situ (DCIS). Nearly all women with this early stage of breast cancer can be cured. DCIS is also called intraductal carcinoma or stage 0 breast cancer. DCIS is a non-invasive or pre-invasive breast cancer.