What is GemCis chemo?

What is GemCis chemo?

Gemcitabine plus cisplatin (GemCis) is the standard first-line chemotherapy for patients with advanced biliary tract cancer (BTC). In ABC-02 study, the BTC patients received up to 6-8 cycles of 3-weekly GemCis; however, those without progression often receive more than 6-8 cycles.

How many cycles of gemcitabine and cisplatin can you have?

You usually have between 4 to 6 cycles of treatment taking from 3 to 6 months.

How long do the side effects of gemcitabine last?

The symptoms are usually self-limiting and recovery is generally within 24 to 48 hours. Less than 1% of patients discontinued use due to flu-like symptoms.

How long can you stay on gemcitabine?

You usually have gemcitabine as a course of several cycles of treatment. This means that you have the drug and then a rest to allow your body to recover. Usually a cycle of gemcitabine is over 3 to 4 weeks (21 to 28 days). You usually have gemcitabine once a week for 2 or 3 weeks and then a week with no treatment.

What is the success rate of gemcitabine?

Treatment with single-agent gemcitabine achieved clinical benefit and symptoms improvement in 20-30% of patients. While 1-year survival was observed in 2% of 5-fluorouracil (5-FU)-treated patients, it was raised to 18% by single-agent gemcitabine.

Will I lose hair on gemcitabine?

You could lose all your hair. This includes your eyelashes, eyebrows, underarm, leg and sometimes pubic hair. Your hair will usually grow back once treatment has finished but it is likely to be softer. It may grow back a different colour or be curlier than before.

Which cancers are treated with cisplatin?

Cisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar platinum-based drugs were developed with National Cancer Institute (NCI) support.

Is cisplatin still used today?

Cisplatin is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar platinum-based drugs were developed with National Cancer Institute (NCI) support. They are prescribed for an estimated 10 to 20 percent of all cancer patients.

What does cisgem stand for?

As a result of our previous NCRN study (ABC-02) cisplatin and gemcitabine (CisGem) is likely to become the international standard of care for patients with advanced biliary tract cancer (submitted: ASCO 2009).

What is the role of cisgem in the workup of cholangiocarcinoma?

CisGem resulted in improved PFS and OS for intra- and extra-hepatic cholangiocarcinomas and gallbladder cancer.

What happened to cisgem?

January 1, 2015 CISGEM was sold by CCIAA Milan to the company Pronto Gold SpA which entrusted CISGEM with the management of FONDAZIONE GEMMOLOGICA ITALIANA – in which CISGEM enters as its own entity thus maintaining its complete and absolute independence from the private and commercial world.

Is cisgem the best first-line treatment for good-Ps patients with advanced BTC?

Conclusions: CisGem is the standard of care for the first-line treatment of good-PS patients with advanced BTC regardless of ethnicity.