What is Chlormethiazole used for?

What is Chlormethiazole used for?

Clomethiazole (chlormethiazole) Clomethiazole is a sedative-hypnotic that has been used extensively in the treatment of alcohol withdrawal, as well as for inducing sedation and sleep in the elderly.

Is Clomethiazole a benzodiazepine?

Clomethiazole is pharmacologically distinct from both the benzodiazepines and the barbiturates. Clomethiazole has sedative, muscle relaxant and anticonvulsant properties.

What is the side effect of methyldopa?

SIDE EFFECTS: Dizziness, lightheadedness, drowsiness, headache, stuffy nose, and weakness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What class of drug is Clomethiazole?

Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal.

What are the contraindications of methyldopa?


  • Active hepatic disease [7]
  • Liver disorders due to previous therapy.
  • Direct Coombs positive hemolytic anemia.
  • Significant drug history of MAO inhibitor therapy.
  • Pheochromocytoma.
  • Known hypersensitivity to methyldopa in any form.

What class of drug is methyldopa?

Methyldopa belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension). High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.

What type of inhibitor is disulfiram?

Disulfiram (DSF) is presently the only available drug used in the aversion therapy of recovering alcoholics. It acts by inhibiting aldehyde dehydrogenase (ALDH), leading to high blood levels of acetaldehyde.

What are contraindications for barbiturates?

Contraindications: Barbiturate sensitivity, liver disease, impaired renal function, patients with severe respiratory distress, respiratory disease in which dyspnea, obstruction or cor pulmonale is present, acute or chronic pain.

What is the antidote for barbiturates?

There is no direct antidote for barbiturates. An antidote is a medicine that reverses the effects of another medicine or drug. In select and extreme cases of overdose, dialysis (kidney machine) may be used to help remove the drug from the blood.

What is mechanism of action of methyldopa?

Mechanism of Action Alpha-methyldopa is converted to methyl norepinephrine centrally to decrease the adrenergic outflow by alpha-2 agonistic action from the central nervous system, leading to reduced total peripheral resistance and decreased systemic blood pressure.

What is the chemical name of methyldopa?


Clinical data
IUPAC name (S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid
CAS Number 41372-08-1 anhydrous: 555-30-6
PubChem CID 38853 anhydrous: 40175