What is a biodegradable polymer give example of a biodegradable polymer which was used for the first time in surgery?
One of the first medicinal uses of a biodegradable polymer was the catgut suture, which dates back to at least 100 AD. The first catgut sutures were made from the intestines of sheep, but modern catgut sutures are made from purified collagen extracted from the small intestines of cattle, sheep, or goats.
Why are polymers good for drug delivery?
Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses over long periods, cyclic dosage, and tunable release of both hydrophilic and hydrophobic drugs.
What are biomedical polymers?
Biomedical polymers are a special class of materials that are designed to work in harmony with the body, and for the basis of a growing number of artificial organs and replacement parts intended for fitting into the human body.
Why polymers are the best suitable material for biomedical applications?
Among these polymers biomedical polymers are specially mentioned due to their less toxicity in vivo, easy to process and sterilized, better shelf life, light weight, and remarkable properties suited to the applications [1].
How are polymers used in drug delivery?
What is polymer based drug delivery?
Polymeric drug delivery system has defined as a formulation or a device that enables the introduction of a therapeutic substance into the body. It improves its safety and efficacy by controlling the rate, time, and place of release of drugs in the body.
Which polymer is used in drug delivery?
Among the synthetic and biodegradable polymers, aliphatic polyesters such as poly (glycolic acid), poly (lactic acid), poly (caprolactone) and polydioxanone, are most commonly used and applied to drug delivery systems.
Which polymers are used for controlled drug release in the body?
Most of the materials used in swelling-controlled release systems are based on hydrogels, which are polymers that will swell without dissolving when placed in water or other biological fluids….
- Polylactides (PLA).
- Polyglycolides (PGA).
- Poly(lactide-co-glycolides) (PLGA).
- Polyanhydrides.
- Polyorthoesters.
What are Bio medical polymers?
What are the types of biomedical polymers?
Natural polymers such as collagen, gelatin, hyaluronic acid, silk fibroin, chitosan, alginate, and PHBV are now frequently used for different biomedical devices because of their excellent biocompatibility.
What is biomedical polymers and their applications?
What are biomedical applications?
Biomedical applications of smart materials can be divided into three categories: (1) implants and stents, such as bone plates and marrow needles; (2) surgical and dental instruments, devices, and fixtures, such as orthodontic fixtures and biopsy forceps; and (3) devices and instruments for medical checkups, such as …
Why are polymers used for drug delivery?
The main role of polymer is to protect drug from physiological environment and prolong release of drug to improve its stability. The drug is release from polymer by diffusion, degradation and swelling.