What does rifampin do to bacteria?
Rifampin is in a class of medications called antimycobacterials. It works by killing the bacteria that cause infection. Antibiotics such as rifampin will not work for colds, flu, or other viral infections.
What is the role of linezolid?
Linezolid is used to treat infections, including pneumonia, and infections of the skin . Linezolid is in a class of antibacterials called oxazolidinones. It works by stopping the growth of bacteria. Antibiotics such as linezolid will not work for colds, flu, and other viral infections.
Which class of drugs has a significant interaction with linezolid?
Linezolid also belongs to a class of drugs known as MAO inhibitors. It can increase the levels of certain natural substances in the body (such as dopamine, norepinephrine, serotonin) which can increase the chance of certain side effects and food and drug interactions.
What does erythromycin interact with?
Several reports and controlled studies have shown that erythromycin may interact with theophylline, carbamazepine, cyclosporin, tacrolimus, warfarin, digoxin, terfenadine, astemazole, cisapride, lovastatin, triazolam, and disopyramide.
What is the main function of erythromycin?
Erythromycin is used to prevent and treat infections in many different parts of the body, including respiratory tract infections, skin infections, diphtheria, intestinal amebiasis, acute pelvic inflammatory disease, Legionnaire’s disease, pertussis, and syphilis.
What is the main use of rifampin?
This medication is a rifamycin antibiotic used to prevent and treat tuberculosis and other infections. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).
What is the target of rifampin?
Rifampin specifically inhibits bacterial RNA polymerase, the enzyme responsible for DNA transcription, by forming a stable drug-enzyme complex with a binding constant of 10(-9) M at 37 C. The corresponding mammalian enzymes are not affected by rifampin.
What does linezolid interact with?
Some products that may interact with this drug include: diet pills/appetite suppressants (such as diethylpropion), drugs for attention deficit disorder (such as atomoxetine, methylphenidate), apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, a certain combination product ( …
What type of bacteria does linezolid treat?
Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA).
What are the contraindications of linezolid?
Who should not take LINEZOLID?
- diarrhea from an infection with Clostridium difficile bacteria.
- pheochromocytoma.
- thyrotoxicosis.
- a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone.
- carcinoid syndrome.
- low amount of sodium in the blood.
What are the different types of pathogens?
Pathogenic organisms are of five main types: viruses, bacteria, fungi, protozoa, and worms. Some common pathogens in each group are listed in the column on the right. Infectious agents can grow in various body compartments, as shown schematically in Fig. 10.4.
What are four modes of pathogen transmission?
The modes (means) of transmission are: Contact (direct and/or indirect), Droplet, Airborne, Vector and Common Vehicle.
What are the contraindications for erythromycin?
Who should not take ERYTHROMYCIN?
- diarrhea from an infection with Clostridium difficile bacteria.
- myasthenia gravis, a skeletal muscle disorder.
- hearing loss.
- torsades de pointes, a type of abnormal heart rhythm.
- prolonged QT interval on EKG.
- abnormal EKG with QT changes from birth.
- liver problems.