What does low pneumococcal titers mean?

What does low pneumococcal titers mean?

Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization.

What are pneumococcal titers?

Pneumococcal Antibody Titers (23 Serotypes), IgG This test measures IgG antibody levels to Streptococcus Pneumoniae to determine how well a person has responded to vaccination.

Is there a titer for pneumococcal vaccine?

Interpretation of the antibody response to the 23-valent pneumococcal vaccine is straightforward if the preimmunization titer for a given serotype is less than 1.3 μg/mL and the postimmunization titer is 1.3 μg/mL or greater….TABLE III.

Serotype OR Preimmunization titer value (μg/mL)
19F 0.16 8.7
23F 0.06 5.5

What does it mean if your antibodies are low?

Low levels of immunoglobulins mean your immune system isn’t working as well as it should. This can be caused by: Medicines that weaken your immune system, such as steroids. Diabetes complications.

Is specific antibody deficiency an autoimmune disease?

Specific antibody deficiency (SAD) is a primary immunodeficiency disease characterized by normal immunoglobulins (Igs), IgA, IgM, total IgG, and IgG subclass levels, but with recurrent infection and diminished antibody responses to polysaccharide antigens following vaccination.

How long do pneumonia antibodies last?

Antibody levels remained elevated for two to nine years after pneumonia but usually fell sharply after the second year in persons with milder symptoms.

What does a high M pneumoniae IgG ABS mean?

What does it mean if your Mycoplasma pneumoniae IgG Abs result is too high? A positive result indicates prior exposure to Mycoplasma. A single positive IgG result may be present in the absence of any clinical symptoms as specific IgG antibodies may remain elevated long after initial infection.

Why are my titers low?

Thus, a person with a severe infection may test negative or have a low titer because of higher numbers of antigen-antibody complexes and lower numbers of free antibodies in the blood. In certain conditions, a low titer may essentially indicate the efficient removal of infectious pathogens by the immune system.

What autoimmune diseases cause high IgA?

Levels of IgA also get higher in some autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (SLE), and in liver diseases, such as cirrhosis and long-term (chronic) hepatitis. IgG. High levels of IgG may mean a long-term (chronic) infection, such as HIV, is present.

Are you immune after getting pneumonia?

The body’s immune system helps fight off harmful bacteria and viruses. A person with a normal, healthy immune system is typically able to recover from pneumonia after treatment with antibiotics and rest.

What is Mycoplasma titer?

Immunofluorescence Titer of IgG and IgM Antibodies Mycoplasmas are small bacteria (0.3 to 0.8 //m in diameter and up to 150 μπι in length) that are unique because they have no cell wall. Two genera, Mycoplasma and Ureaplasma (associated with genital infections), are of clinical importance to humans.

What is a normal Mycoplasma level?

Reference Range: Mycoplasma pneumoniae Antibody, IgG < 0.10 U/L: Negative 0.10-0.32 U/L: Equivocal > 0.32 U/L: Positive Mycoplasma pneumoniae Antibody, IgM <0.76 U/L or less: Negative-No clinically significant amount of M. pneumoniae antibody detected. 0.77-0.95 U/L: Equivocal-M.