What are the limitation of Conventional drug delivery system?

What are the limitation of Conventional drug delivery system?

Conventional drug delivery systems contain numerous limitations such as limited targeting, low therapeutic indices, poor water solubility, and the induction of drug resistances.

What are the advantages of novel drug delivery method over conventional drug delivery method?

Advantage: 1) They are natural part of body, so they are biodegradable in nature. 3) The entrapment of drug also does not require the chemical modification of the substance to be entrapped. 4) They are non immunogenic in action and can be targeted to disease tissue/organ..

What are the advantages and disadvantages of controlled drug delivery systems?

Table 4

Advantages of Controlled DDS Disadvantages of Controlled DDS
Long residence of drug Invasive procedure to implant or remove the system
Protection from metabolism by enzymes/chemicals Uptake by RES reduces efficacy
Improved bioavailability Poorer IVIVC
Low dosing frequency Limited standards

What is the drawback of parenteral controlled release system?

What is the drawback of parental controlled release systems? Explanation: The major drawback of parenteral administration is once the administration is done, the drug cannot be removed easily if an undesirable action happens. If the drug gets precipitated or not needed any more it cannot be removed from our body.

What are different types of novel drug delivery system?

The development of several types of NDDS in the last few decades includes (Microparticles, Nanoparticles, Liposomes, Niosomes, Transdermal drug delivery, Microencapsulation) with the motive of delivering drugs to targeted tissue to cure certain diseases.

What does novel drug mean?

Novel drugs are often innovative products that serve previously unmet medical needs or otherwise significantly help to advance patient care and public health. NMEs have chemical structures that have never been approved before.

What are the advantages and disadvantages of targeted drug delivery system?

Advantages: Convenience in Administration, Non invasive, accurate dose, Higher compliance, Economical [8 – 10]. Disadvantages: Unconscious patients cannot take dose, Low solubility and permeability, Degradation by Gastro Intestinal flora, first pass metabolism, Food interactions, and Poor bioavailability.

Why is targeted drug delivery better?

The advantages to the targeted release system is the reduction in the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of drug side-effects, and reduced fluctuation in circulating drug levels.

Which of the following is not a disadvantage of site specific drug delivery?

Which of the following is not a disadvantage of site-specific drug delivery? Explanation: Less distribution time is an advantage for the drug.

What is delayed release system?

Delayed release. Delayed-release dosage forms can be defined as systems which are formulated to release the active ingredient at a time other than immediately after administration.

What is the meaning of novel drug?

How many types of drug delivery systems are there?

Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles, cargo, and targeting strategies. Medications can be taken in a variety of ways—by swallowing, by inhalation, by absorption through the skin, or by intravenous injection.

Which is an orphan drug?

An orphan drug is a pharmaceutical agent developed to treat medical conditions which, because they are so rare, would not be profitable to produce without government assistance.

Which of the following is a disadvantage of control drug delivery system?

What are the disadvantages of nanotechnology to the fields of medicine?

Some of the disadvantages of nanotechnology are: (a) It is very expensive and its developing cost is high; (b) Its manufacturing is difficult [1-4]. The usage of nanotechnology in different areas of medicine is called nanomedicine.

What are some of the problems with the printgravure printer?

Gravure printing problems include a limited number of inks with which it’s compatible. In most cases, flexo printing ink is the superior choice due to the ease of printing with a wider variety of inks. Gravure requires much more ink per print, which can drive up the cost of printing.

What is the use of a gravure printer?

Gravure printing is an expensive and high quality printing that uses direct contact between etched copper plate printing rollers and the paper. It is most often reserved for printing wall coverings and the like. What has the author Tariq Hulou written?

What is the difference between rotogravure and gravure?

Flexo is noted for producing exemplary print with fine line and text detail. The rotogravure printing process (commonly shortened to gravure) is a method of intaglio printing. Gravure printing works by applying ink to a substrate with the use of a metal plate that is typically mounted onto a cylinder.

What is the difference between Flexo and gravure image carriers?

Gravure image carriers are typically much more expensive than flexo image carriers, making the number of prints required to break even much higher. Gravure, however, has a longer press run time, as the cylinders do not require as frequent changing as those in the flexo printing process.