What does RPGN mean?
Rapidly progressive glomerulonephritis (RPGN) is a clinical and pathological syndrome; a term used to describe the following: Rapid loss of renal function over a very short period (days to weeks) Nephritic urine analysis: proteinuria, micro or macroscopic hematuria, dysmorphic red blood cells (RBC), RBC casts.
What is the difference between acute glomerulonephritis and RPGN?
RPGN describes a clinical syndrome of rapid loss of renal function over days to weeks in patients with evidence of glomerulonephritis. In contrast, crescentic nephritis is a histopathologic description of kidney biopsy specimens that demonstrate the presence of crescents in more than 50% of glomeruli.
What is non proliferative glomerulonephritis?
Non-proliferative glomerulonephritis is characterised by a lack of glomerular cell proliferation and typically presents with nephrotic syndrome. Proliferative glomerulonephritis is characterised by increased numbers of cells in the glomerulus. It typically presents with nephritic syndrome.
How do you classify glomerulonephritis?
Membranous lupus nephritis was classified as class V….CLASSIFICATION OF LUPUS NEPHRITIS: HISTORY.
| Class I | Normal glomeruli (by LM, IF, EM) |
|---|---|
| Class III | Focal proliferative glomerulonephritis (<50%) |
| Class IV | Diffuse proliferative glomerulonephritis (≥50%) |
| Class V | Membranous glomerulonephritis |
What is a glomerulonephritis?
Glomerulonephritis is inflammation and damage to the filtering part of the kidneys (glomerulus). It can come on quickly or over a longer period of time. Toxins, metabolic wastes and excess fluid are not properly filtered into the urine. Instead, they build up in the body causing swelling and fatigue.
How is RPGN diagnosed?
Testing includes serum creatinine, urinalysis, complete blood count (CBC), serologic tests, and renal biopsy. Diagnosis is usually by serologic tests and renal biopsy. Serum creatinine is almost always elevated. Urinalysis shows hematuria is always present, and RBC casts are usually present.
What is rapidly progressive glomerulonephritis RPGN?
Rapidly progressive glomerulonephritis (RPGN) is a clinical syndrome manifested by features of glomerular disease in the urinalysis and by progressive loss of kidney function over a comparatively short period of time (days, weeks, or a few months).
What are the two types of glomerulonephritis?
There are two types of glomerulonephritis—acute and chronic. The acute form develops suddenly. You may get it after an infection in your throat or on your skin….The early symptoms of the acute disease are:
- puffiness of your face in the morning.
- blood in your urine (or brown urine)
- urinating less than usual.
What are the types of glomerulonephritis?
There are two types of glomerulonephritis—acute and chronic. The acute form develops suddenly. You may get it after an infection in your throat or on your skin.
What is BOR syndrome?
Branchiootorenal (BOR) syndrome is characterized by pits or ear tags in front of the outer ear (preauricular pits), abnormal passages from the throat to the outside surface of the neck (branchial fistulas), branchial cysts, malformations of the outer, middle and inner ear, hearing loss and kidney (renal) abnormalities.
What is the most common type of RPGN?
ANCA-associated GN, or pauci-immune crescentic GN, is the most common form of RPGN, accounting for 80% of cases. This entity lacks tissue immune deposits though the glomerular disease is mediated by an immunologic mechanism.
Is RPGN reversible?
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
What is the meaning of glomerulonephritis?
(gloh-MAYR-yoo-loh-neh-FRY-tis) A condition in which the tissues in the kidney become inflamed and have problems filtering waste from the blood. Glomerulonephritis may be caused by infection, inflammatory conditions (such as lupus), certain genetic conditions, and other diseases or conditions.
What is another name for glomerulonephritis?
Glomerulonephritis is a group of diseases that injure the part of the kidney that filters blood (called glomeruli). Other terms you may hear used are nephritis and nephrotic syndrome.